Risks and Benefits of Thrombolytic, Antiplatelet, and Anticoagulant Therapies for ST Segment Elevation Myocardial Infarction: Systematic Review
نویسندگان
چکیده
منابع مشابه
Risks and Benefits of Thrombolytic, Antiplatelet, and Anticoagulant Therapies for ST Segment Elevation Myocardial Infarction: Systematic Review
Objectives. Assess the impact of associating thrombolytics, anticoagulants, antiplatelets, and primary angioplasty (PA) on death, reinfarction (AMI), and major bleeding (MB) in STEMI therapy. Methods. Medline search was performed to identify randomized trials comparing these classes in STEMI treatment, at least 500 patients, providing death, AMI, and MB rates. Similar arms were grouped. Correla...
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The results of the ER-TIMI (Thrombolysis in Myocardial Infarction) 19 trial (1) provide yet another building block in the case for prehospital administration of thrombolytic agents to patients presenting with acute ST-segment elevation myocardial infarction (MI). These results reflect as accurately as possible the contemporary impact on time to administration (32-min decrease), and they come at...
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Adjunctive anticoagulant therapy reduces the risk of recurrent infarction and death in patients with STsegment elevation myocardial infarction (STEMI) receiving fibrinolytic therapy.1–5 Unfractionated heparin (UFH), the first anticoagulant evaluated for this indication,1 continues to be used because of its predominantly nonrenal clearance, short half-life, reversibility, and the familiarity of ...
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Background and Objective: One of the most important advancements regarding the care of patients with acute myocardial infarction is the administration of anti-coagulation medicines (e.g., streptokinase). However, it must be noticed that this medicine requires rapid and timely administration. Moreover, Percutaneous Coronary Intervention (PCI) is increasingly used as a method of revascularization...
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Acute ST-segment elevation myocardial infarction (STEMI) is a serious disease in clinical practice. The rapid and accurate diagnosis of this critical illness can lead to prompt reperfusion, and it enables the reduction of cardiac ischemic damage and results in improved subsequent outcomes. The shorter the time to reperfusion, the greater the benefits. The American College of Cardiology/American...
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ژورنال
عنوان ژورنال: ISRN Cardiology
سال: 2014
ISSN: 2090-5599
DOI: 10.1155/2014/416253